Ethyl 4-isocyanatobenzoate → HCID 66905365, compound

HRID 1690509Notes

Reaction equation

HRID 1690509 reaction equation
[CH:1]1([NH:7][C:8]2[N:9]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[N:10]=[C:11]3[C:16]=2[CH:15]=[CH:14][CH:13]=[CH:12]3)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:23]([O:25][C:26](=[O:36])[C:27]1[CH:32]=[CH:31][C:30]([N:33]=[C:34]=[O:35])=[CH:29][CH:28]=1)[CH3:24]>C1(C)C=CC=CC=1>[CH2:23]([O:25][C:26](=[O:36])[C:27]1[CH:32]=[CH:31][C:30]([NH:33][C:34]([N:7]([CH:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)[C:8]2[N:9]([C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)[N:10]=[C:11]3[C:16]=2[CH:15]=[CH:14][CH:13]=[CH:12]3)=[O:35])=[CH:29][CH:28]=1)[CH3:24]

Participants

4

Reactant 2

HCID 589805Ethyl 4-isocyanatobenzoateHCID 12318206N-Cyclohexyl-2-phenyl-2H-indazol-3-amine

Product 1

HCID 66905365HCID 66905365, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In analogy to the procedure described in example 1.2, cyclohexyl-(2-phenyl-2H-indazol-3-yl)-amine (example 1.1) was reacted with 4-isocyanato-benzoic acid ethyl ester ([30806-83-8]) in toluene to give the title compound as yellow solid. MS: m/e=483.3 [M+H+].

Sources & evidence

ORD record
ord-9107d1bdd1ca495b92cedf2396eeeffd
Source dataset
uspto-grants-2012_04
Patent number
US08153663B2

Reaction notes

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