Cyclohexyl isocyanate → 1-Butyl-1-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-3-cyclohexyl-urea

HRID 1690512Notes

Reaction equation

HRID 1690512 reaction equation
[CH2:1]([NH:5][C:6]1[N:7]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)[N:8]=[C:9]2[C:14]=1[CH:13]=[CH:12][CH:11]=[CH:10]2)[CH2:2][CH2:3][CH3:4].[CH:22]1([N:28]=[C:29]=[O:30])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>>[CH2:1]([N:5]([C:6]1[N:7]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)[N:8]=[C:9]2[C:14]=1[CH:13]=[CH:12][CH:11]=[CH:10]2)[C:29]([NH:28][CH:22]1[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1)=[O:30])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 18502Cyclohexyl isocyanateHCID 66905446butyl-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-amine

Product 1

HCID 451106161-Butyl-1-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-3-cyclohexyl-urea

Procedure

In analogy to the procedure described in example 1.2, butyl-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-amine was reacted with cyclohexylisocyanate ([3173-53-3]) to give the title compound as yellow solid. MS: m/e=425.3 [M+H+].

Sources & evidence

ORD record
ord-f2350aa8c89f4f6cac57c9a25bea3c50
Source dataset
uspto-grants-2012_04
Patent number
US08153663B2

Reaction notes

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