HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Cyclohexyl-2-phenyl-2H-indazol-3-amine → 3-Chloro-4-[3-cyclohexyl-3-(2-phenyl-2H-indazol-3-yl)-ureido]-benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Cyclohexyl-2-phenyl-2H-indazol-3-amine | HCID 12318206 | — |
| Reactant | 3-Chloro-4-isocyanato-benzoic acid methyl ester | HCID 86640262 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 3-Chloro-4-[3-cyclohexyl-3-(2-phenyl-2H-indazol-3-yl)-ureido]-benzoic acid methyl ester | HCID 66905722 | — |
Reaction Steps
In analogy to the procedure described in example 1.2, cyclohexyl-(2-phenyl-2H-indazol-3-yl)-amine (example 1.1) was reacted with 3-chloro-4-isocyanato-benzoic acid methyl ester (example 9.1) in toluene for 4 days under reflux conditions to give the title compound as white solid. MS: m/e=503.0 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153663B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-f99e3eea58504a84a2ebe5e78f00af73 |
| Source note | uspto-grants-2012_04 |