Triethylamine → (4-{3-[2-(4-Chloro-phenyl)-2H-indazol-3-yl]-3-cyclohexyl-ureido}-3-fluoro-phenoxy)-acetic acid methyl ester

Participants

Reaction Steps

In analogy to the procedure described in example 1.2, [2-(4-chloro-phenyl)-2H-indazol-3-yl]-cyclohexyl-amine (example 9.1) was reacted with (3-fluoro-4-isocyanato-phenoxy)-acetic acid methyl ester (example 24.1) in 1,2-dichloroethane in the presence of Et3N (2.2 eq.) for 3 days under reflux conditions to give the title compound as brown gum. MS: m/e=551.3 [M+H+].

Provenance & Evidence