HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 45111769, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 66905435 | HCID 66905435 | — |
| Solvent | iPrOAc brine | HCID 131729614 | — |
| Product | HCID 45111769 | HCID 45111769 | — |
Reaction Steps
In analogy to the procedure described in example 2.2, 3-chloro-4-[3-cyclohexyl-3-(2-phenyl-4,5,6,7-tetrahydro-2H-indazol-3-yl)-ureido]-benzoic acid methyl ester was treated with 1 N aqueous lithium hydroxide solution in THF/MeOH 1/1 for 1 h at ambient temperature to give the title compound as yellow solid. MS: m/e=493.3 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153663B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-9dc3c0e0088448cabb77fcc0303bb1f0 |
| Source note | uspto-grants-2012_04 |