反应详情

1-{3-(3-methoxypropoxy)-4-[(triisopropylsilyl)oxy]phenyl}ethanol (12.5 g, 32.7 mmol) was dissolved in toluene (1200 mL) and manganese dioxide (74.7 g, 860 mmol) was added. The mixture was brought to reflux for 7 hrs. The mixture was then filtered off and the solvent was evaporated to yield 9.8 g (quantitative yield) of the desired product as an oil.

1. temperatureto reflux for 7 hrs
2. filtrationThe mixture was then filtered off
3. customthe solvent was evaporated