Aminopyrazine → 2-bromo-N-(pyrazin-2-yl)acetamide

HRID 1690641Notes

Reaction equation

HRID 1690641 reaction equation
[Br:1][CH2:2][C:3]([NH:5][C:6]1[CH:10]=CO[N:7]=1)=[O:4].[NH2:11][C:12]1[CH:17]=NC=CN=1>>[Br:1][CH2:2][C:3]([NH:5][C:6]1[CH:10]=[N:11][CH:12]=[CH:17][N:7]=1)=[O:4]

Participants

3

Reactant 2

HCID 78747AminopyrazineHCID 133629192-bromo-N-(isoxazol-3-yl)acetamide2×

Product 1

HCID 445426692-bromo-N-(pyrazin-2-yl)acetamide

Procedure

This compound is prepared by an analogous method to 2-bromo-N-isoxazol-3-yl-acetamide (Intermediate A) by replacing 3-aminoisoxazole with 2-aminopyrazine

Sources & evidence

ORD record
ord-51952628c70248d29fea4977d38dbd81
Source dataset
uspto-grants-2012_04
Patent number
US08153669B2

Reaction notes

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