HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Piperidinol, 1-methyl- → 4-Hydroxy-1-(isoxazol-3-ylcarbamoylmethyl)-1-methyl-piperidinium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Piperidinol, 1-methyl- | HCID 66048 | — |
| Reactant | (1R/S,3R)-3-Hydroxy-1-(isoxazol-3-ylcarbamoylmethyl)-1-methyl-piperidinium bromide | HCID 87357711 | — |
| Product | 4-Hydroxy-1-(isoxazol-3-ylcarbamoylmethyl)-1-methyl-piperidinium bromide | HCID 87197983 | — |
Reaction Steps
This compound is prepared by an analogous method to (1R/S,3R)-3-Hydroxy-1-(isoxazol-3-ylcarbamoylmethyl)-1-methyl-piperidinium bromide (Intermediate C) by replacing (R)-1-methyl-piperidin-3-ol (step C3) with 1-methyl-piperidin-4-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153669B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-65cb00622ea840f48918ed91b7e5cea0 |
| Source note | uspto-grants-2012_04 |