HuagongsheHuagongshe Chemistry Print Report · For research reference only
alpha-Cyclopentylmandelic acid → 4-(2-Cyclopentyl-2-hydroxy-2-phenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl methyl)-1-methyl-piperidinium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | alpha-Cyclopentylmandelic acid | HCID 98283 | — |
| Reactant | 4-(2-Cyclohexyl-2-hydroxy-2-phenyl-acetoxy)-1-(isoxazol-3-ylcarbamoylmethyl)-1-methyl-piperidinium bromide | HCID 87197905 | — |
| Product | 4-(2-Cyclopentyl-2-hydroxy-2-phenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl methyl)-1-methyl-piperidinium bromide | HCID 87197946 | — |
Reaction Steps
This compound is prepared by an analogous method to 4-(2-cyclohexyl-2-hydroxy-2-phenyl-acetoxy)-1-(isoxazol-3-ylcarbamoylmethyl)-1-methyl-piperidinium bromide (Example 3) by replacing cyclohexyl-hydroxy-phenyl-acetic acid with cyclopentyl-mandelic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153669B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-f6f214291db44327a1d6b2742e5af11c |
| Source note | uspto-grants-2012_04 |