Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1690699Generated: October 30, 2026

5-amino-2,3-dihydro-1H-inden-1-one → 7-(4-Butylphenyl)-6-fluoro-5,10-dihydroindeno[1,2-b]indol-2-amine

https://huagongshe.com/reaction/1690699

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-amino-2,3-dihydro-1H-inden-1-oneHCID 312890—
ReactantHCID 66904900HCID 66904900—
Product7-(4-Butylphenyl)-6-fluoro-5,10-dihydroindeno[1,2-b]indol-2-amineHCID 5761851517%

Reaction Steps

The title material is prepared in 17% yield by reacting 5-Amino-indan-1-one (commercially available) and (4′-Butyl-2-fluoro-biphenyl-3-yl)-hydrazine hydrochloride (Example 78, step) in an analogous manner to example 1, step 3; LC/MS calculated for [M+H]+ C25H23FN2: 371.2, found: 371.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08153671B2
Source datasetuspto-grants-2012_04
ORD IDord-f8928caa98f244bc81e88b861f047d17
Source noteuspto-grants-2012_04