HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-amino-2,3-dihydro-1H-inden-1-one → 7-(4-Butylphenyl)-6-fluoro-5,10-dihydroindeno[1,2-b]indol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-amino-2,3-dihydro-1H-inden-1-one | HCID 312890 | — |
| Reactant | HCID 66904900 | HCID 66904900 | — |
| Product | 7-(4-Butylphenyl)-6-fluoro-5,10-dihydroindeno[1,2-b]indol-2-amine | HCID 57618515 | 17% |
Reaction Steps
The title material is prepared in 17% yield by reacting 5-Amino-indan-1-one (commercially available) and (4′-Butyl-2-fluoro-biphenyl-3-yl)-hydrazine hydrochloride (Example 78, step) in an analogous manner to example 1, step 3; LC/MS calculated for [M+H]+ C25H23FN2: 371.2, found: 371.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153671B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-f8928caa98f244bc81e88b861f047d17 |
| Source note | uspto-grants-2012_04 |