Oxiranemethanol, 4-methylbenzenesulfonate, (S)- → HCID 86650225, compound
Reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[C:13]([C:15]([F:18])([F:17])[F:16])[CH:12]=[CH:11][C:10]=1[OH:19])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:20](OS(C1C=CC(C)=CC=1)(=O)=O)[C@H:21]1[O:23][CH2:22]1>>[CH2:1]([O:8][C:9]1[CH:14]=[C:13]([C:15]([F:16])([F:17])[F:18])[CH:12]=[CH:11][C:10]=1[O:19][CH2:20][C@H:21]1[CH2:22][O:23]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
The title compound was prepared from compound C and (S)-glycidyl-p-toluene sulfonate (B) employing the procedure used for the preparation of compound 5′.
Sources & evidence
- ORD record
- ord-657d93a797a74b0086c9d100e592eba6
- Source dataset
- uspto-grants-2012_04
- Patent number
- US08153651B2
Reaction notes
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