Ethanol → 7-fluoro-3-(piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([N:14]2[C:15](=[O:25])[NH:16][c:17]3[cH:18][c:19]([F:24])[cH:20][cH:21][c:22]3[CH2:23]2)[CH2:12][CH2:13]1.[CH3:26][CH2:27][O:28][CH2:29][CH3:30].[CH3:31][CH2:32][OH:33].[Pd:34]>>[NH:8]1[CH2:9][CH2:10][CH:11]([N:14]2[C:15](=[O:25])[NH:16][c:17]3[cH:18][c:19]([F:24])[cH:20][cH:21][c:22]3[CH2:23]2)[CH2:12][CH2:13]1Participants
5
Sources & evidence
- ORD record
- ord-e926f8345ba544eeab5751a4facfd5e6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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