HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → HCID 24991591, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 3-HYDROXY-2-PHENYLPROPIONITRILE | HCID 11008065 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 24991591 | HCID 24991591 | 98% |
Reaction Steps
A sample of this 2-phenyl-3-hydroxypropanenitrile (127 mg, 0.863 mmol) and acetic anhydride (106 μL, 1.1 mmol) in acetonitrile (250 μL) was treated with sulfuric acid (˜0.5 μL). After 25 min at ambient temperature, work-up as described above in Example 5 gave 160 mg (98%) product as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153688B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-f81da038f5dd4415ab9284f24762c7eb |
| Source note | uspto-grants-2012_04 |