Methyl 4-hydroxypyrrolidine-2-carboxylate → 1-(5'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carbonyl)-4-hydroxy-pyrrolidine-2-carboxylic acid methyl ester
Reaction equation
[CH2:1]([CH3:2])[c:3]1[cH:4][c:5](-[c:11]2[cH:12][n:13][cH:14][c:15]([C:17](=[O:18])[OH:19])[cH:16]2)[c:6]([CH3:10])[nH:7][c:8]1=[O:9].[CH3:20][O:21][C:22](=[O:23])[CH:24]1[NH:25][CH2:26][CH:27]([OH:29])[CH2:28]1>>[CH2:1]([CH3:2])[c:3]1[cH:4][c:5](-[c:11]2[cH:12][n:13][cH:14][c:15]([C:17](=[O:19])[N:25]3[CH:24]([C:22]([O:21][CH3:20])=[O:23])[CH2:28][CH:27]([OH:29])[CH2:26]3)[cH:16]2)[c:6]([CH3:10])[nH:7][c:8]1=[O:9]Participants
3
Sources & evidence
- ORD record
- ord-64451cb5908044bc90440ff75b3e4f88
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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