HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-(5-Chloro-furan-2-ylmethyl)-phenyl)-methanol → HCID 59255186, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-(5-Chloro-furan-2-ylmethyl)-phenyl)-methanol | HCID 59255370 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59255186 | HCID 59255186 | 83% |
Reaction Steps
To a mixture of (4-(5-chloro-furan-2-ylmethyl)-phenyl)-methanol (650 mg, 2.9 mmol) described in Manufacturing Example 62-1-3 and dichloromethane (20 mL) was added manganese dioxide (6.5 g, 75 mmol) at room temperature, which was stirred overnight at room temperature. The reaction mixture was filtered through a Celite pad. The filtrate was evaporated under a reduced pressure to obtain the title compound (530 mg, 83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153662B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-fa2fc6ac7b5a49469168ac2d8584129b |
| Source note | uspto-grants-2012_04 |