2-Fluoro-6-(trifluoromethyl)benzoyl chloride → propyl 2-{[2-fluoro-6-(trifluoromethyl)benzoyl]amino}-5,6,7,8-tetrahydro-4H-5,8-epoxycyclohepta[b]thiophene-3-carboxylate
Reaction equation
[F:19][c:20]1[c:21]([C:22](=[O:23])[Cl:24])[c:25]([C:29]([F:30])([F:31])[F:32])[cH:26][cH:27][cH:28]1.[NH2:1][c:2]1[c:3]([C:13](=[O:14])[O:15][CH2:16][CH2:17][CH3:18])[c:4]2[c:5]([s:6]1)[CH:7]1[CH2:8][CH2:9][CH:10]([CH2:11]2)[O:12]1>>[NH:1]([c:2]1[c:3]([C:13](=[O:14])[O:15][CH2:16][CH2:17][CH3:18])[c:4]2[c:5]([s:6]1)[CH:7]1[CH2:8][CH2:9][CH:10]([CH2:11]2)[O:12]1)[C:22]([c:21]1[c:20]([F:19])[cH:28][cH:27][cH:26][c:25]1[C:29]([F:30])([F:31])[F:32])=[O:23]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-790e47dc2e26463486b1d612955da51f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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