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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1691444Generated: November 1, 2026

Dimethyl malonate → HCID 59618618, compound

https://huagongshe.com/reaction/1691444

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl malonateHCID 7943—
Reactant8-bromo-6-[(4-tert-butylphenyl)sulfonyl]-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepineHCID 59618636—
ProductHCID 59618618HCID 59618618—

Reaction Steps

Intermediate 53 was reacted with dimethyl malonate following the procedure as described in Hartwig, John F. (JOC 2002, 67, 541-555) to afford the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08153626B2
Source datasetuspto-grants-2012_04
ORD IDord-7ffe329bbd1844d6a67f7fbcab2a8e8e
Source noteuspto-grants-2012_04