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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1692017Generated: October 29, 2026

Thionyl Chloride → 6-Bromopyridine-2-carbonyl chloride

https://huagongshe.com/reaction/1692017

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant6-Bromopyridine-2-carboxylic acidHCID 593919—
Product6-Bromopyridine-2-carbonyl chlorideHCID 15661724—

Reaction Conditions

Temperature70 °C

Reaction Steps

A mixture of 6-bromo-2-pyridinecarboxylic acid (1 g, 5 mmol) in SOCl2 (10 ml, 140 mmol) was heated to 70° C. for 6 hours and concentrated to dryness to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08153813B2
Source datasetuspto-grants-2012_04
ORD IDord-6c27eb5d3c294a1bb71ae388f6f9025c
Source noteuspto-grants-2012_04