HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1-Pyrrolidinyl)piperidine → HCID 57580526, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1-Pyrrolidinyl)piperidine | HCID 78703 | — |
| Reactant | 4-Bromo-2-methylbenzoic acid | HCID 99570 | — |
| Reactant | 3-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) | HCID 2734385 | — |
| Reactant | HCID 65573179 | HCID 65573179 | — |
| Reactant | HCID 66901611 | HCID 66901611 | — |
| Product | HCID 57580526 | HCID 57580526 | — |
Reaction Steps
In analogy to the procedure described for example 1, (4-bromo-2-methyl-phenyl)-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone (prepared from 4-bromo-2-methyl-benzoic acid and 4-pyrrolidin-1-yl-piperidine in analogy to the procedure described for the preparation of intermediate 2) was reacted with 3-trifluoromethoxy-phenyl boronic acid to give the title compound as light yellow solid. MS: 433.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153805B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-5c66ac75559c43f29e6f09767e7faaaf |
| Source note | uspto-grants-2012_04 |