Potassium Phosphate, Tribasic → HCID 57580531, compound

Participants

Reaction Steps

In analogy to the procedure described for example 1, (4-bromo-2-chloro-phenyl)-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone (prepared from 4-bromo-2-chloro-benzoic acid and 4-pyrrolidin-1-yl-piperidine in analogy to the procedure described for the preparation of intermediate 2), was reacted with 3-trifluoromethyl-phenyl boronic acid, potassium phosphate solution and tetrakis-(triphenylphosphine)-palladium in DMF while keeping the temperature at RT instead of 80° C. to give the title compound as light brown oil. MS: 437.2 (MH+, 1Cl).

Provenance & Evidence