Potassium Phosphate, Tribasic → HCID 57580530, compound

Participants

Reaction Steps

In analogy to the procedure described in example 1, (4-bromo-2-methanesulfonyl-phenyl)-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone (prepared from 4-bromo-2-methanesulfonyl-benzoic acid and 4-pyrrolidin-1-yl-piperidine in analogy to the procedure described for the preparation of intermediate 2) was reacted with 3-trifluoromethyl-phenyl boronic acid, potassium phosphate solution and tetrakis-(triphenylphosphine)-palladium in DMF at 80° C. to give the title compound as light yellow oil. MS: 481.2 (MH+).

Provenance & Evidence