HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Amino-3-chloro-4-methoxyphenyl)ethanone → N-(6-acetyl-2-chloro-3-methoxyphenyl)-4-isopropylthiazole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Amino-3-chloro-4-methoxyphenyl)ethanone | HCID 29919988 | — |
| Reactant | N-(6-Acetyl-3-methoxy-2-methylphenyl)-4-(propan-2-yl)-1,3-thiazole-2-carboxamide | HCID 53482122 | — |
| Product | N-(6-acetyl-2-chloro-3-methoxyphenyl)-4-isopropylthiazole-2-carboxamide | HCID 56605150 | — |
Reaction Steps
The title product 51 was prepared (79%) from (2-amino-3-chloro-4-methoxyphenyl)-(methyl)ketone (50) following the procedure reported for 2′-[[(4-isopropylthiazole-2-yl)(oxo)methyl]amino]-4′-methoxy-3′-methylacetophenone (35): m/z=353 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153800B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-e07eb7454c534cca8bd2b7fd90dfde9a |
| Source note | uspto-grants-2012_04 |