Acetic Acid → HCID 87336924, compound

HRID 1692631Notes

Reaction equation

HRID 1692631 reaction equation
[CH3:1][C:2]1[C:7]2[C:8]([O:10][C:11]3[C:12]([CH3:23])=[C:13]([O:21][CH3:22])[CH:14]=[C:15]([C:18]([OH:20])=[O:19])[C:16]=3[O:17][C:6]=2[C:5]([CH:24]=[O:25])=[C:4](O)[CH:3]=1)=[O:9].[C:27](O)(=[O:29])[CH3:28]>N1C=CC=CC=1>[C:27]([C:4]1[CH:3]=[C:2]([CH3:1])[C:7]2[C:8](=[O:9])[O:10][C:11]3[C:12]([CH3:23])=[C:13]([O:21][CH3:22])[CH:14]=[C:15]([C:18]([OH:20])=[O:19])[C:16]=3[O:17][C:6]=2[C:5]=1[CH:24]=[O:25])(=[O:29])[CH3:28]

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 23725Psoromic Acid

Product 1

HCID 87336924HCID 87336924, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Psoromic acid (1 mmol) was dissolved in pyridine (2 ml) and glacial acetic acid (1 ml). The reaction was stirred for 14 hours at room temperature. Most of the solvent was removed by rotatory evaporation. The residue was taken up in methylene chloride, washed with water and saturated brine, dried with anhydrous MgSO4, evaporated by a rotatory evaporator and purified by column chromatography.

Workup

  1. customMost of the solvent was removed by rotatory evaporation
  2. washwashed with water and saturated brine
  3. dry with materialdried with anhydrous MgSO4
  4. customevaporated by a rotatory evaporator
  5. custompurified by column chromatography

Sources & evidence

ORD record
ord-19bb619f527f488d848659f0d3a114d8
Source dataset
uspto-grants-2012_04
Patent number
US08158623B2

Reaction notes

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