Water → Dibenzo[b,e][1,4]oxazepin-11(5H)-one

Participants

Reaction Steps

A solution of 2-(2-Hydroxy-phenylamino)-benzoic acid (2.0 g, 9 mmol) and p-toluenesulfonic acid (0.5 g) in toluene (200 ml) was heated under N2 with the H2O formed being collected in a Dean-Stark receiver. Upon completion, the organic layer was washed with saturated NaHCO3, dried over anhydrous MgSO4, filtered, and evaporated by a rotatory evaporator to obtain the product (1.0 g, 53%).

Provenance & Evidence