huagongshe.com
HRID1692680

反应详情

EQUATION

反应方程式

HRID 1692680 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2ccc(N)nc2)OC1(C)C
HCID2756555

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

C11H17BN2O2

结构：Cn1c(C(C)(C)O)nc2c(N3CCOCC3)nc(Cl)nc21
HCID58015213

未命名化合物

PRODUCTS

生成物

1
结构：Cn1c(C(C)(C)O)nc2c(N3CCOCC3)nc(-c3ccc(N)nc3)nc21
HCID44543768

未命名化合物

PROCEDURE

实验过程

2-(2-Chloro-9-methyl-6-morpholino-9H-purin-8-yl)propan-2-ol (95 mg) was reacted with 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine via Procedure A and purified via reverse phase HPLC to give 89.3 mg of 131 as a white solid. MS (Q1) 370.3 (M)+

WORKUP

后处理

  1. custompurified via reverse phase HPLC