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HRID1692696

反应详情

EQUATION

反应方程式

HRID 1692696 的结构方程式

REACTANTS

反应物

4
结构：CC(C)CI
HCID10556

Propane, 1-iodo-2-methyl-

C4H9I

结构：CC(C)(C)c1c(OC(=O)[O-])cccc1B1OC(C)(C)C(C)(C)O1
HCID53421896

未命名化合物

结构：CC(C)Cn1cnc2c(N3CCOCC3)nc(Cl)nc21
HCID58015219

未命名化合物

结构：Clc1nc(N2CCOCC2)c2nc[nH]c2n1
HCID178478374

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)Cn1cnc2c(N3CCOCC3)nc(-c3cccc(O)c3)nc21
HCID44544109

未命名化合物

PROCEDURE

实验过程

4-(2-Chloro-9H-purin-6-yl)morpholine (75 mg) was reacted with 1-iodo-2-methylpropane via General Procedure C. 4-(2-Chloro-9-isobutyl-9H-purin-6-yl)morpholine was reacted with 150 mg tert-butyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl carbonate via General Procedure A and purified via reverse phase HPLC to give 62.6 mg of 145 as a white solid. MS (Q1) 354.2 (M)+

WORKUP

后处理

  1. custompurified via reverse phase HPLC