HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Morpholinoethylamine → HCID 86630080, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Morpholinoethylamine | HCID 408285 | — |
| Reactant | 5-Chloro-2-(methylsulfonyl)-7-morpholinothiazolo[4,5-d]pyrimidine | HCID 57685406 | — |
| Product | HCID 86630080 | HCID 86630080 | — |
Reaction Steps
5-Chloro-2-(methylsulfonyl)-7-morpholinothiazolo[4,5-d]pyrimidine was reacted with 2-morpholinoethanamine via General Procedure C to give crude 5-chloro-7-morpholino-N-(2-morpholinoethyl)thiazolo[4,5-d]pyrimidin-2-amine, which was then reacted with 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine via General Procedure C again to give 136 after purification by reverse HPLC. MS (Q1) 444 (M+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158626B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-9202b0a17b144f758985fbbd1ae0ae66 |
| Source note | uspto-grants-2012_04 |