p-Toluenesulfonic acid → HCID 66824283, compound

Participants

Reaction Steps

To a mixture of 2,2′-(3,3-dimethoxycyclobutane-1,1-diyl)diacetonitrile (2 g, 0.01 mol) in acetone (5 mL) was added p-toluenesulfonic acid (1 g, 0.006 mol). The mixture was stirred at rt over weekend. The reaction was neutralized with aq. saturated NaHCO3 solution, extracted with EtOAc. The combined organic layers were washed with brine, dried over MgSO4 and evaporated to give a crude product as brown oil.

Provenance & Evidence