4-(Pyridin-4-yl)aniline → HCID 24966320, compound

Participants

Reaction Steps

To a solution of (4-pyridine-4-yl)aniline (CAS: 13296-04-3, 0.290 g) in dichloromethane (12.0 ml) was added 5-fluoro-3-methylbenzo[b]thiophene-2-sulphonyl chloride (0.440 g) and DMAP (0.305 g). The reaction mixture was stirred at rt for 16 h, diluted with dichloromethane (12 ml) and chromatographed on silica gel using heptane/ethyl acetate as eluent to obtain the title compound (0.205 g) as an off-white solid. MS (ISN): 397.1 (M−H)−

Provenance & Evidence