反应详情

A solution of 4-[4-(5-fluoro-3-methyl-benzo[b]thiophene-2-sulfonylamino)-3-methanesulfonyl-phenyl]-piperidine-1-carboxylic acid tert-butyl ester (0.025 g) in ethyl acetate (1 ml) was treated with 2.5 N HCl/ethyl acetate (2 ml). The reaction mixture was stirred at rt for 2 h. Ether (20 ml) was added, the precipitate was filtered off, washed with ether and dried under high vacuum over P2O5 to obtain the title compound (0.020 g) as a yellowish powder. MS (ISP): 483.3 (M+H)+

1. filtrationthe precipitate was filtered off
2. washwashed with ether
3. dry with materialdried under high vacuum over P2O5