HCID 14457752, compound → HCID 24966679, compound

Participants

Reaction Steps

To a solution of 2-methanesulfonyl-4-pyridin-4-yl-phenylamine (cf. Example 20c, 0.27 g) and 6-fluoro-naphthalene-2-sulfonyl chloride (0.148 g; cf. Brown, George Robert; Stokes, Elaine Sophie Elisabeth; Waterson, David; Wood, Robin. WO 9706802) in dichloromethane (1.0 ml) was added DMAP (0.037 g). The reaction mixture was stirred at rt for 2 h and directly chromatographed on silica gel using heptane/ethyl acetate as eluent to produce the title compound (0.098 g) as a colorless foam. MS (ISP): 457.3 (M+H)+

Provenance & Evidence