1,3-Dibromo-5-chlorobenzene → HCID 57827618, compound

HRID 1693233Notes

Reaction equation

HRID 1693233 reaction equation
F[C@H]1CC[C@:5]2([C:20]3[CH:25]=[CH:24]C=CC=3F)[N:6]=[C:7]([NH:10]C(=O)OC(C)(C)C)[S:8][CH2:9][C@@H:4]2C1.Br[C:28]1[CH:33]=[C:32]([Cl:34])[CH:31]=[C:30]([Br:35])[CH:29]=1>>[Br:35][C:30]1[CH:29]=[C:28]([C@:5]23[CH2:20][CH2:25][CH2:24][C@H:4]2[CH2:9][S:8][C:7]([NH2:10])=[N:6]3)[CH:33]=[C:32]([Cl:34])[CH:31]=1

Participants

3

Reactant 2

HCID 846761,3-Dibromo-5-chlorobenzeneHCID 86633533HCID 86633533, compound

Product 1

HCID 57827618HCID 57827618, compound

Procedure

The title compound was synthesized from hex-5-enal oxime (JOC, 41 (5), 863-9; 1976) according to the method of Preparation Example 8, using 1,3-dibromo-5-chlorobenzene instead of 2-fluorobromobenzene.

Workup

  1. customaccording to the method of Preparation Example 8

Sources & evidence

ORD record
ord-e4f5f31c45fd4685970635128c1e9c46
Source dataset
uspto-grants-2012_04
Patent number
US08158620B2

Reaction notes

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