Isobutylamine → HCID 59311538, compound

Participants

Reaction Steps

Reaction and post-treatment were performed in the same manner as in Example 18 using 4-amino-N-(3-chloropropyl)-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-7,8-dihydro-2H-6-thia-1,2,3,5-tetraazaacenaphthylene-7-carboxamide of Example 17 (30 mg) and isobutylamine (2 mL), followed by purification by NH silica gel column chromatography (dichloromethane-methanol) to obtain the title compound (20 mg, 62%) as a solid.

Provenance & Evidence