Anisole → HCID 178508146, compound

Participants

Reaction Steps

Anisole (2.5 ml) and trifluoroacetic acid (30 ml) were added to the above di-tert-butyl {2-(4-methoxybenzyl)-7,8-dihydro-2H-6-thia-1,2,3,5-tetraazaacenaphthylen-4-yl}imidodicarbonate (6.0 g). The mixture was stirred at room temperature for 16 hours and then stirred at 55° C. for six hours. The reaction solution was concentrated under reduced pressure. Ethyl acetate was added to the resulting residue, followed by stirring. The precipitated solid was filtered off and washed with ethyl acetate to obtain the title compound (1.75 g, 78%) as a solid.

Provenance & Evidence