Potassium Carbonate → HCID 59311575, compound

Participants

Reaction Conditions

Reaction Steps

A mixture composed of the above 7,8-dihydro-2H-6-thia-1,2,3,5-tetraazaacenaphthylen-4-amine (30 mg), 2-(chloromethyl)quinoline hydrochloride (51 mg), potassium carbonate (98 mg) and dimethylformamide (1 mL) was stirred at 60° C. overnight. The insoluble matter was separated off by filtration, and then the solvent was evaporated in a nitrogen stream. The residue was purified by reversed phase liquid chromatography (acetonitrile-formic acid) to obtain the title compound (19 mg, 35%) as an amorphous.

Provenance & Evidence