HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Isothiocyanate → 4-Benzyl-2-(4-methoxybenzyl)-[1,2,4]thiadiazolidine-3,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Isothiocyanate | HCID 2346 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Isocyanic acid, p-methoxybenzyl- | HCID 187910 | — |
| Product | 4-Benzyl-2-(4-methoxybenzyl)-[1,2,4]thiadiazolidine-3,5-dione | HCID 11602336 | — |
Reaction Steps
Reagents: Benzylisothiocyanate (6.5 mmol, 0.85 mL), p-methoxybenzyl-isocyanate (6.5 mmol, 0.92 mL) and SO2Cl2 (6.5 mmol, 0.52 mL) in diethyl ether (25 mL). Isolation: solvent evaporation. Purification: silica gel column chromatography (AcOEt/hexane, 1:4).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158661B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-222d598e7f114cf38c4e22cf0aa04d01 |
| Source note | uspto-grants-2012_04 |