HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1694232Generated: October 30, 2026
Acetic Acid → (E)-1-(Benzyloxy)-4-(2-nitrovinyl)benzene
https://huagongshe.com/reaction/1694232
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Nitromethane | HCID 6375 | — |
| Reactant | Benzaldehyde, 4-(phenylmethoxy)- | HCID 78109 | — |
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Solvent | Water | HCID 962 | — |
| Product | (E)-1-(Benzyloxy)-4-(2-nitrovinyl)benzene | HCID 5702926 | 97.9% |
Reaction Steps
To a mixture of 4-benzyloxy benzaldehyde (50 g, 0.24 mol) and acetic acid (200 mL) were added nitromethane (64 mL, 1.2 mol) and ammonium acetate (36 g, 0.47 mol), which was stirred for 90 minutes at 100° C. The reaction mixture was cooled to room temperature, and water (1 L) was added at the same temperature. The deposited solids were filtered to obtain the title compound (60 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08158657B2 |
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| Source dataset | uspto-grants-2012_04 |
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| ORD ID | ord-f4938501f7d84796847f3b088a90b752 |
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| Source note | uspto-grants-2012_04 |
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