HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59186879, compound → HCID 59186880, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59186879 | HCID 59186879 | — |
| Reactant | HCID 178445911 | HCID 178445911 | — |
| Product | HCID 59186880 | HCID 59186880 | 8% |
Reaction Steps
The title compound was prepared using General method A starting from (2R)-2-[(2-amino-5-mercapto[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-4-methylpentan-1-ol (860 mg, 2.87 mmol) and 3-chloro-4-[(1R)-1-chloroethyl]pyridine from the previous step. Purification by flash chromatography yielded the title compound (105 mg, 8% yield) as a diastereomeric mixture.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158785B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-caf254a6667c4e60b413833b5a0ec8a5 |
| Source note | uspto-grants-2012_04 |