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HRID1694555

反应详情

EQUATION

反应方程式

HRID 1694555 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)c1cc(C#N)ccn1
HCID10464460

2-ACETYL-ISONICOTINONITRILE

C8H6N2O

结构：C[C@@H]1[C@H](B(Cl)[C@@H]2C[C@H]3C[C@@H]([C@@H]2C)C3(C)C)C[C@H]2C[C@@H]1C2(C)C
HCID86625794

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](O)c1cc(C#N)ccn1
HCID59868824

未命名化合物

收率 30.8%

PROCEDURE

实验过程

The title compound was prepared according to General Method B starting from 2-acetyl-isonicotinonitrile (2.00 g, 13.7 mmol) and (−)-DIPCl (6.58 g, 20.53 mmol) to yield the title compound (625 mg, 4.22 mmol) with 90% ee.

WORKUP

后处理

  1. customThe title compound was prepared