HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 59156757, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Tetrabutylammonium Hydroxide | HCID 2723671 | — |
| Reactant | 3-Bromo-5-tert-butyl-2-hydroxybenzaldehyde | HCID 7172096 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59156757 | HCID 59156757 | — |
Reaction Steps
step 1—Benzylation of 3-bromo-5-tert-butyl-2-hydroxy benzaldehyde (36a) with benzyl bromide is accomplished treating 36a with benzyl bromide and tetrabutylammonium hydroxide in a biphasic system comprised of MeOH and DCM to afford 2-benzyloxy-3-bromo-5-tert-butyl-benzaldehyde (36b).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158803B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-bb031bc928fe4e9daaacb285d3b1c19d |
| Source note | uspto-grants-2012_04 |