HCID 67280484, compound → HCID 23540778, compound

HRID 1694695Notes

Reaction equation

HRID 1694695 reaction equation
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][C:10]=1[C:16]1[CH:17]=[N:18][CH:19]=[N:20][CH:21]=1)C1C=CC=CC=1>[Pd].C(O)C>[Cl:15][C:12]1[CH:13]=[CH:14][C:9]([OH:8])=[C:10]([C:16]2[CH:21]=[N:20][CH:19]=[N:18][CH:17]=2)[CH:11]=1

Participants

4

Reactant 1

HCID 67280484HCID 67280484, compound

Product 1

HCID 23540778HCID 23540778, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of the product from step (iii) (0.28 g), 10% palladium on carbon (0.04 g) in ethanol (20 ml) was hydrogenated at 2 Bar for 24 h. After filtration the solvent was evaporated under reduced pressure. Yield 0.19 g

Workup

  1. filtrationAfter filtration the solvent
  2. customwas evaporated under reduced pressure

Sources & evidence

ORD record
ord-7278a3884c834d2db2f61300767f4802
Source dataset
uspto-grants-2012_04
Patent number
US08158820B2

Reaction notes

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