Morpholine → HCID 123464039, compound

HRID 1694698Notes

Reaction equation

HRID 1694698 reaction equation
[Cl:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])=[C:4]([C:17]2[C:18]([CH3:27])=[N:19][C:20](S(C)(=O)=O)=[N:21][CH:22]=2)[CH:3]=1.[NH:28]1[CH2:33][CH2:32][O:31][CH2:30][CH2:29]1>O1CCOCC1>[C:11]([O:10][C:8](=[O:9])[CH2:7][O:6][C:5]1[CH:15]=[CH:16][C:2]([Cl:1])=[CH:3][C:4]=1[C:17]1[C:18]([CH3:27])=[N:19][C:20]([N:28]2[CH2:33][CH2:32][O:31][CH2:30][CH2:29]2)=[N:21][CH:22]=1)([CH3:14])([CH3:13])[CH3:12]

Participants

4

Reactant 2

HCID 8083MorpholineHCID 91272087HCID 91272087, compound

Product 1

HCID 123464039HCID 123464039, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A solution of the product from step (vii) (0.15 g) and morpholine (0.15 ml) in dioxane (3 ml) was heated at 90° C. for 24 h, cooled and the solvent evaporated under reduced pressure.

Workup

  1. temperaturecooled
  2. customthe solvent evaporated under reduced pressure

Sources & evidence

ORD record
ord-7df58ce931af4eaf8d3943363166f333
Source dataset
uspto-grants-2012_04
Patent number
US08158820B2

Reaction notes

Loading…