(5-Chloro-2-hydroxyphenyl)boronic Acid (contains varying amounts of Anhydride) → HCID 67280036, compound
Reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH3:10])=[CH:4][C:3]=1[C:11]([F:14])([F:13])[F:12].[Cl:15][C:16]1[CH:17]=[CH:18][C:19]([OH:25])=[C:20](B(O)O)[CH:21]=1>>[Cl:15][C:16]1[CH:17]=[C:18]([C:2]2[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH3:10])=[CH:4][C:3]=2[C:11]([F:14])([F:13])[F:12])[C:19]([OH:25])=[CH:20][CH:21]=1Participants
3
Procedure
The subtitle compound was prepared by the method of example 1 step (ii) using the product from step (i) and 5-chloro-2-hydroxyphenyl-boronic acid, yield 0.26 g
Sources & evidence
- ORD record
- ord-533a98dfb7864a4f8e458f8866422864
- Source dataset
- uspto-grants-2012_04
- Patent number
- US08158820B2
Reaction notes
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