(5-Chloro-2-hydroxyphenyl)boronic Acid (contains varying amounts of Anhydride) → HCID 67280146, compound
Reaction equation
Br[C:2]1[CH:3]=[N:4][C:5]([N:8]([CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[C:9](=[O:11])[CH3:10])=[N:6][CH:7]=1.[Cl:19][C:20]1[CH:21]=[CH:22][C:23]([OH:29])=[C:24](B(O)O)[CH:25]=1>>[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([OH:29])=[C:22]([C:2]2[CH:3]=[N:4][C:5]([N:8]([CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:9](=[O:11])[CH3:10])=[N:6][CH:7]=2)[CH:21]=1Participants
3
Procedure
The subtitle compound was prepared by the method of example 1 step (ii) using the product from step (i) and 5-chloro-2-hydroxyphenyl-boronic acid, yield 0.16 g.
Sources & evidence
- ORD record
- ord-c9a3313a92e84add847c54c9415921d5
- Source dataset
- uspto-grants-2012_04
- Patent number
- US08158820B2
Reaction notes
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