HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Bromobenzenesulfonyl chloride → 1-(4-Bromobenzene-1-sulfonyl)pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Bromobenzenesulfonyl chloride | HCID 7396 | — |
| Reactant | Pyrrolidine | HCID 31268 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-(4-Bromobenzene-1-sulfonyl)pyrrolidine | HCID 738618 | — |
Reaction Steps
A solution of 4-bromobenzenesulphonyl chloride (0.5 g) and pyrrolidine (0.284 g) in acetonitrile (5 ml) were stirred at RT for 48 h then partitioned between ethylacetate and water. The organics were separated, washed with water, dried and evaporated under reduced pressure. The residue was triturated with isohexane and filtered, yield 0.5 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158820B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-f702b8bd7fff4025a58502bcb39fb7f7 |
| Source note | uspto-grants-2012_04 |