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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1694728Generated: October 31, 2026

p-Bromobenzenesulfonyl chloride → 1-(4-Bromobenzene-1-sulfonyl)pyrrolidine

https://huagongshe.com/reaction/1694728

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Bromobenzenesulfonyl chlorideHCID 7396—
ReactantPyrrolidineHCID 31268—
SolventAcetonitrileHCID 6342—
Product1-(4-Bromobenzene-1-sulfonyl)pyrrolidineHCID 738618—

Reaction Steps

A solution of 4-bromobenzenesulphonyl chloride (0.5 g) and pyrrolidine (0.284 g) in acetonitrile (5 ml) were stirred at RT for 48 h then partitioned between ethylacetate and water. The organics were separated, washed with water, dried and evaporated under reduced pressure. The residue was triturated with isohexane and filtered, yield 0.5 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08158820B2
Source datasetuspto-grants-2012_04
ORD IDord-f702b8bd7fff4025a58502bcb39fb7f7
Source noteuspto-grants-2012_04