3-Bromobenzonitrile → HCID 11404887, compound

HRID 1694740Notes

Reaction equation

HRID 1694740 reaction equation
B([C:4]1[CH:15]=[C:14]([C:16]([F:19])([F:18])[F:17])[CH:13]=[CH:12][C:5]=1[O:6][C@@H:7]([CH3:11])[C:8]([OH:10])=[O:9])(O)O.Br[C:21]1[CH:22]=[C:23]([CH:26]=[CH:27][CH:28]=1)[C:24]#[N:25]>>[C:24]([C:23]1[CH:22]=[C:21]([C:4]2[CH:15]=[C:14]([C:16]([F:19])([F:18])[F:17])[CH:13]=[CH:12][C:5]=2[O:6][C@@H:7]([CH3:11])[C:8]([OH:10])=[O:9])[CH:28]=[CH:27][CH:26]=1)#[N:25]

Participants

3

Reactant 2

HCID 233813-BromobenzonitrileHCID 67277101(2S)-2-[2-borono-4-(trifluoromethyl)phenoxy]-propanoic acid

Product 1

HCID 11404887HCID 11404887, compound

Procedure

The title compound was prepared by the method of example 144 step (i) using the product from step (iv) and 3-bromobenzonitrile.

Sources & evidence

ORD record
ord-4e48c7fd9b254b82af751d73fef5f47d
Source dataset
uspto-grants-2012_04
Patent number
US08158820B2

Reaction notes

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