4-Bromo-N,N-dimethylbenzenesulphonamide → HCID 58333660, compound

HRID 1694741Notes

Reaction equation

HRID 1694741 reaction equation
B([C:4]1[CH:15]=[C:14]([C:16]([F:19])([F:18])[F:17])[CH:13]=[CH:12][C:5]=1[O:6][C@@H:7]([CH3:11])[C:8]([OH:10])=[O:9])(O)O.Br[C:21]1[CH:26]=[CH:25][C:24]([S:27]([N:30]([CH3:32])[CH3:31])(=[O:29])=[O:28])=[CH:23][CH:22]=1>>[CH3:31][N:30]([CH3:32])[S:27]([C:24]1[CH:23]=[CH:22][C:21]([C:4]2[CH:15]=[C:14]([C:16]([F:19])([F:18])[F:17])[CH:13]=[CH:12][C:5]=2[O:6][C@@H:7]([CH3:11])[C:8]([OH:10])=[O:9])=[CH:26][CH:25]=1)(=[O:28])=[O:29]

Participants

3

Reactant 2

HCID 128184-Bromo-N,N-dimethylbenzenesulphonamideHCID 67277101(2S)-2-[2-borono-4-(trifluoromethyl)phenoxy]-propanoic acid

Product 1

HCID 58333660HCID 58333660, compound

Procedure

The title compound was prepared by the method of example 144 step (i) using the product from example 146 step (iv) and 4-bromo-N,N-dimethyl-benzenesulfonamide.

Sources & evidence

ORD record
ord-723373b97782436db42186a6ed721e5b
Source dataset
uspto-grants-2012_04
Patent number
US08158820B2

Reaction notes

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