HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-[2-borono-4-(trifluoromethyl)phenoxy]-propanoic acid → 2-[[2'-Chloro-4'-[(dimethylamino)sulfonyl]-5-(trifluoromethyl)[1,1'-biphenyl]-2-yl]oxy]-(2S)-propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-[2-borono-4-(trifluoromethyl)phenoxy]-propanoic acid | HCID 67277101 | — |
| Reactant | 3-Chloro-4-iodo-N,N-dimethylbenzenesulfonamide | HCID 67280204 | — |
| Product | 2-[[2'-Chloro-4'-[(dimethylamino)sulfonyl]-5-(trifluoromethyl)[1,1'-biphenyl]-2-yl]oxy]-(2S)-propanoic acid | HCID 11476492 | — |
Reaction Steps
The title compound was prepared by the method of example 144 step (i) using the product from step (ii) and the product from example 146 step (iv).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158820B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-9dd2adb4d5c140d6955b8e9b625e2da3 |
| Source note | uspto-grants-2012_04 |