HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-N,N-dimethylbenzenesulphonamide → [[5-Chloro-4'-[(dimethylamino)sulfonyl][1,1'-biphenyl]-2-yl]oxy]-(2s)-propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-N,N-dimethylbenzenesulphonamide | HCID 12818 | — |
| Reactant | (2S)-2-(2-borono-4-chlorophenoxy)-propanoic acid | HCID 67277298 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | [[5-Chloro-4'-[(dimethylamino)sulfonyl][1,1'-biphenyl]-2-yl]oxy]-(2s)-propanoic acid | HCID 11429045 | — |
Reaction Steps
The title compound was prepared by the method of example 144 step (i) using the product from step (iv) and 4-bromo-N,N-dimethylbenzenesulfonamide and THF as solvent. Yield (0.068 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158820B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-9b4d93441cba419b8d4b27d060596aed |
| Source note | uspto-grants-2012_04 |