HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-((4-Bromophenyl)sulfonyl)azetidine → 2-[[4'-(1-Azetidinylsulfonyl)-5-chloro[1,1'-biphenyl]-2-yl]oxy]-(2s)-propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-((4-Bromophenyl)sulfonyl)azetidine | HCID 7213242 | — |
| Reactant | (2S)-2-(2-borono-4-chlorophenoxy)-propanoic acid | HCID 67277298 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-[[4'-(1-Azetidinylsulfonyl)-5-chloro[1,1'-biphenyl]-2-yl]oxy]-(2s)-propanoic acid | HCID 11749805 | — |
Reaction Steps
The title compound was prepared by the method of example 144 step (i) using the product from example 151 step (iv), 1-[(4-bromophenyl)sulfonyl]azetidine and THF as solvent. Yield 0.028 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158820B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-238b2211693e4c3ab23a7914dc2149f1 |
| Source note | uspto-grants-2012_04 |